Researchers introduce a new tool for more accurate RNA modification detection from nanopore signals

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called ...

Seattle’s Parse Biosciences to be acquired by Qiagen for $225M

Seattle's Parse Biosciences is teed up for an acquisition by Qiagen, a Netherlands-based holding company, in a $225 million ...
The Scientist

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.
IEEE

Contrastive Representation Learning for Multimodal Single-Cell RNA-Seq Data Integration

Abstract: MultiVI, a model for multimodal single-cell data generation, alongside an SSL contrastive learning pipeline is the foundation of this research. The combination approach promotes better ...
Precision Medicine Online

Genetic Testing Challenges in Precision Medicine: DNA, RNA Sequencing Picks Up Intronic NF1 Variant

A man with neurofibromas who didn't know he's been clinically diagnosed with NF1, learns he harbors a deeply intronic, likely ...
IEEE

GRNNLink: Predicting gene regulatory links from single-cell RNA-seq data using graph recurrent neural network

Abstract: Single-cell RNA sequencing (scRNA-seq) technology offers unprecedented opportunities for inferring gene regulatory networks (GRNs) at the genome level. However, scRNA-seq data is highly ...
SciTech Daily

New Tool Reads DNA and RNA in a Single Cell, Unlocking Secrets of Disease

For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...
Frontiers

Integrative RNA-seq and LASSO-COX analysis reveal Paeonol’s key target gene in proliferation suppression and apoptosis-induced in cervical cancer

1 Department of Obstetrics and Gynecology, The First Affiliated Hospital of Dalian Medical University, Dalian, China 2 Department of General Surgery, The First Affiliated Hospital of Dalian Medical ...